Wellness for physical, emotional & psychological wellbeing is maintained

Wellness

Wellness is more than the absence of disease.

It is a process of change towards a balanced state where the physical, emotional & psychological well being is maintained and preserved. Our goal is to arrive at a unique wellness signature by measuring, monitoring and maintaining wellness though quantitation and customised solutions.

Panel of Wellness Management Packages

Wellness Management

Basic Wellness

Advance Wellness

Brain Health

Liver Health

Kidney Health

Bone Health

Inflammation

Heart Health/CVS

Metabolic Disorders

The 5W’s of Wellness Biomarkers

Wellness Biomarkers

What

A biomarker is a measurable indicator of the severity or presence of some disease state or some other physiological state of an organism. Small changes in these biomarker levels may be indicative of big changes in health status.

Where & How

Levels of biomarkers will be determined at Dabur Research Foundation by multiplex technology. Luminex Magpix™ (multi-analyte profiling) technology enables rapid and accurate detection and quantitation of multiple secreted proteins (cytokines, chemokines, growth factors, etc).

When

To be prescribed after first meeting with doctors and to be monitored periodically during the course of treatment to track the performance. Customized biomarker panels maybe available as per the requirement of the medical practitioners.

Why

The conventional biochemical diagnostics are necessary and useful to identify the presence of specific disease conditions. However, there is an unmet need for serum biomarkers that provide vital information on overall physical and mental wellness which can be used for advising on intervention required for enhancement of state of wellness in subjects.

Who

The well worried segment.

Family history of lifestyle diseases
The Cardiometabolic disease segment
Intent to receive personalised wellness
Sports Enthusiast
Subjects in recovery from state of illnesses

Glial Cell Derived Neurotrophic Factor (GDNF)

GDNF is a small protein that potently promotes the survival of many types of neurons (cells of the nervous system), that transmit information to other nerve cells, muscle, or gland cells.

Intercellular Adhesion Molecule 1 (ICAM-1)

In neuro degenerative disorders (for example multiple sclerosis, MS), the Blood Brain Barrier (BBB) becomes impaired.

Myeloperoxidase (MPO)

Myeloperoxidase (MPO) is a peroxidase enzyme that shows unwanted effects by indirectly increasing the formation of reactive nitrogen species (RNS), reactive oxygen species (ROS), and tumor necrosis factor alpha (TNF-α), leading to inflammation and oxidative stress.

Beta-NGF

Beta-Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide that is primarily involved in the regulation of growth, maintenance, proliferation and survival of neurons.

S100B

S100 Calcium binding protein B (S100B) is a neurotrophic factor and neuronal survival protein that plays a crucial role in the brain function such as axogenesis, memory, CNS development, neurite extension, astrocyte differentiation, synaptic transmission, positive regulation of myelination etc.

Park7/DJ-1

Protein deglycase DJ-1, protects neurons against oxidative stress and cell death.

CD-40

Inflammation plays a key role in the pathogenesis of cardiovascular disorders.

D-dimer

D-dimer is a product of fibrin degradation. It is a small protein fragment formed in the blood after a blood clot is degraded by fibrinolysis (the process where a blood clot gets dissolved in the body).

Galectin-3

Galectin-3 is a protein, which is secreted by macrophages (immune cells) that plays an important role in cell-cell adhesion, cell-matrix interactions, macrophage activation, angiogenesis, metastasis, cell-repair and apoptosis.

Cardiac myoglobin

Myoglobin is a small, iron and oxygen-binding protein found in heart and skeletal muscles.

L-selectin

L-selectin is an adhesion protein that is constitutively expressed on the immune cells (neutrophils and lymphocytes).

Angiogenin

Angiogenin is a protein that is a potent stimulator of new blood vessels formation through a process called angiogenesis.

Angiopoietin-like protein-3

Angiopoietin-like 3 (ANGPTL3) is a main regulator of lipoprotein metabolism.

Interferon-gamma (IFN-)

Elevated IFN - gamma levels are indicative of cellular inflammation which is seen in certain disease conditions such as infections, allergic responses, celiac disease, liver diseases like hepatitis/hepato, splenic diseases/hepatic fibrosis.

Interleukin-8 (IL-8)

Interleukin-8 is a cytokine produced by numerous cell types including inflammatory cells, keratinocytes, fibroblasts, and endothelial cells.

Tumor Necrosis Factor-alpha (TNF-α)

TNF-α is not usually detectable in a healthy host, but levels become elevated in several inflammatory and infectious conditions.

C-Reactive Protein (CRP)

C-reactive protein (CRP) is an acute phase reactant, a protein synthesized by the liver that is released into the blood within a few hours after tissue injury, the start of an infection or other inflammation.

C-Peptide

The connecting peptide, or C-peptide, is a short polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule.

Insulin

Insulin is an anabolic hormone that is produced and stored in the beta cells of the pancreas.

Leptin

Leptin is a hormone produced by adipose cells and the small intestine, which helps to regulate energy balance by inhibiting hunger.

Myeloperoxidase (MPO)

MPO is a peroxidase enzyme that shows unwanted effects by indirectly increasing the formation of reactive nitrogen species (RNS), reactive oxygen species (ROS), and tumor necrosis factor alpha (TNF-α) leading to inflammation and oxidative stress.

Intercellular adhesion molicule-1 (ICAM-1)

ICAM-1 is a transmembrane adhesion molecule, which is typically expressed on endothelial cells and cells of the immune system.

Adiponectin

Adiponectin is a protein hormone involved in regulating glucose levels as well as fatty acid breakdown.

Adiponectin-like 3 (ANGPTL3)

ANGPTL3 is a main regulator of lipid and lipoprotein metabolism. ANGPTL3 genes are associated with plasma levels of triglycerides (Tgs), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C).

C-reactive protein (CRP)

CRP is an acute phase reactant, a protein synthesized by the liver that is released into the blood within a few hours after tissue injury.

Fibroblast growth factor 23 (FGF-23)

FGF-23 is a protein which is responsible for phosphate and vitamin D metabolism.

Galectin-3

Galectin-3 is a protein, which is secreted by macrophages (immune cells) that plays an important role in cell-cell adhesion, cell-matrix interactions, macrophage activation, angiogenesis.